Associate Director, Drug Product Development

Thryv Therapeutics Inc. is a privately owned company based in Montreal, Quebec, Canada.  Thryv Therapeutics is pioneering a precision medicine approach to treat various diseases, including genetic and drug-induced Long QT Syndromes, atrial fibrillation and heart failure, with potent and selective inhibitors of Serum Glucocorticoid inducible Kinase.

OPPORTUNITY SUMMARY

The Associate Director, Drug Product Development will play a pivotal role in advancing our therapeutic innovations through the formulation and development of drug products from the pre-IND to the clinical stages. They will be responsible for overseeing the design, optimization, and validation of drug product processes while ensuring alignment with regulatory standards and company objectives. Responsibilities encompass collaboration with external partners for preclinical drug product development, technology transfer, scale-up, packaging, labelling, registration batch manufacture, validation, launch, ongoing manufacturing support, and continuous process improvements. This role will report directly to the Senior Director, Product and Process Development.

KEY RESPONSIBILITIES

  • Lead the design and execution of formulation development strategies for pre-IND and clinical-stage compounds.

  • Oversee formulation studies, process development, and optimization for diverse drug product formats, including manufacturing process, scalability, analytical testing, and stability protocols.

  • Coordinate with external partners to develop and implement labelling and packaging strategies for drug products. Ensure compliance with regulatory requirements and industry standards for labelling and packaging materials.

  • Work closely with Regulatory Affairs to ensure alignment with regulatory requirements and contribute to regulatory submissions.

  • Effectively manage timelines, resources, and budgets to achieve project milestones.

  • Serve as a technical expert and keep current in the field of formulation and drug product development.

  • Be able to work independently to drive results and advance projects.

QUALIFICATIONS

EDUCATION AND WORK EXPERIENCE

  • PhD/master’s degree in chemistry, chemical engineering, pharmaceutical sciences, or related field.

  • A minimum of 5 years’ experience in the pharmaceutical industry working in drug product development at pre-IND to commercial stage.

TECHNICAL KNOWLEDGE AND SKILLS

  • Thorough understanding of cGMPs.

  • Expertise in formulation development for various drug product formats (tablets, suspensions, capsules).

  • Experience in process development, scale-up, and technology transfer to manufacturing.

NON-TECHNICAL SKILLS AND COMPETENCIES

  • Exudes the highest level of integrity and an acute sense of ethics.

  • Operates with a sense of urgency and perseverance to achieve results.

  • Ability and enthusiasm to work in a cross-functional team environment.

  • Superior organizational skills and the ability to multi-task and prioritize competing assignments.

  • Excellent oral/written communication, interpersonal, organizational and presentation skills.

  • Proactive and self-motivated, with the ability to work independently with minimal supervision.

  • Ability to work under pressure to meet deadlines.

EQUAL OPPORTUNITY WORKPLACE

Thryv Therapeutics is proud to be an equal opportunity employer. We are committed to equal employment opportunity regardless of race, colour, religion, sex, sexual orientation, gender identity, age, national origin, disability, and any other characteristic protected by law.

APPLY

Please send your resume and cover letter to admin@thryvtrx.com.